The Site Settings page is broken up into different sections, each focusing on a different part of the setup of your store. Depending on what your needs are, you may find not all sections or all prompts need to be set addressed. It is a good idea to review the tool tips and/or documentation to see if any changes to the defaults are necessary. Listed below are the different sections and each is linked to a document that addresses just that particular section.
In addition to these different areas on the main Settings page, you will see that there are also additional tabs that address other functionalities. Make sure to save any changes you make on the main page or any of the tabbed areas before exiting this area. Listed below are the tabs you will find here: